It is a defect of the red cell membrane( -
a) Thalassemia.
b) Sickle cell anemia.
c) Hereditary spherocytosis.=
d) Megaloblastic anemia.

4) All of the following is correct regarding spherocytosis…except:
a) Normocytic Normochromic anemia.
b) Decreased reticulocyte count.=
c) Raised plasma bilirubin.
d) Increased osmotic fragility.

5) Heinz bodies in the red cells are seen in cases of:
a) Hereditary sherocytosis.
b) Hereditary elliptocytosis.
c) Glucose-6-phosphate dehydrogenase deficiency.=
d) Sickle cell anemia.

6) ………………….is caused by substitution of one amino acid (valine) instead of glutamic acid at position no.6 in the beta chain of hemoglobin:
a) Hb-A.
b) Hb-A2.
c) Hb-F.
d) Hb-S.=

7) Atrophy of the spleen, is seen in cases of:
a) Thalassemia.
b) Sickle cell anemia.=
c) G6PD deficiency.
d) Hereditary elliptocytosis.

8) Iron deficiency lead to:
a) Normocytic Normochromic anemia.
b) Microcytic hypochromic anemia.=
c) Macrocytic anemia.
d) Hemolytic anemia.

9) Neurological symptoms are seen in cases of:
a) Iron deficiency anemia.
b) Folic acid deficiency.
c) Vitamin B12 deficiency.=
d) All of the above.

10) Schilling test is done to diagnose of:
a) Sickle cell anemia.
b) Thalassemia.
c) Pernicious anemia.=
d) Folic acid deficiency.

11)Megaloblastic hematopoiesis is seen in cases of :
a) Iron deficiency.
b) Folic acid deficiency.=
c) G6PD deficiency.
d) Vitamin C deficiency.

12) Fanconi's anemia is a type of:
a) Vitamin B12 deficiency.
b) Aplastic anemia.=
c) Thalassemia.
d) Folic acid deficiency anemia.

13) The most abundant leukocyte in a normal blood smear:
a) Lymphocytes.
b) Monocytes.
c) Eosinophils.
d) Neutrophils. =

14) The first line of defence against parasites:
a) Neutrophils.
b) Basophils.
c) Eosinophils.=
d) Lymphocytes.

15) ………………play a role in immediate and delayed hypersensetivity:
a) Monocytes.
b) Lymphocytes.
c) Eosinophils.
d) Basophils. =

16) The largest leukocyte is:
a) Neutrophil.
b) Lymphocyte.
c) Monocyte.=
d) Basophil.

17) Cell which participates in cell-mediated immunity:
a) Monocyte.
b) B-lymphocyte.
c) T-lymphocyte.=
d) Neutrophil.

18) …………….promotes blood clotting and help to prevent blood loss from damaged blood vessels:
a) Platelets.=
b) WBCs.
c) RBCs.
d) All of the above.

19) ………………converts fibrinogen to fibrin:
a) Prothrombin.
b) Thrombin.=
c) Plasminogen.
d) Plasmin.

20) Antibody-induced haemolytic disease in the new born that is caused by blood group incompatibility between mother and fetus:

a) Hemolytic ureamic syndrome.
b) Erythroblastosis fetalis.=
c) Hereditary spherocytosis.
d) Thrombotic thrombocytopenic purpura.

21) Ovalocytes are seen in cases of:
a) Iron deficiency anemia.=
b) Thalassemia.
c) Folate deficiency.
d) All of the above.

22) Red cell with central dark area:
a) Stomatocyte.
b) Spherocyte.
c) Target cell.=
d) Teardrop cell.

23) Young red cell with cytoplasmic RNA:
a) Spherocyte.
b) Reticulocyte.=
c) Stomatocyte.
d) Elliptocyte.

24) The specific haemoglobin binding protein in the plasma is:
a) Bilirubin.
b) Haptoglobin.=
c) Myoglobin.
d) None of the above.

25) Acute blood loss usually results in:
a) Microcytic hypochromic anemia.
b) Normocytic normochromic anemia.=
c) Macrocytic anemia.
d) None of the above.

26) Normal adult haemoglobin tetramer is:
a) 2 alpha: 2 gama. =
b) 2 alpha: 2 beta.
c) 2 alpha: 2 delta.
d) 2 beta : 2 gama.

27)…………………..represent 2 – 4 % of total leukocyte:
a) Neutrophils.
b) Basophils.
c) Eosinophils. =
d) Monocytes.

28) ………………..are small cytoplasmic fragments derived from megakaryocyte:
a) RBCs.
b) WBCs.
c) Platelets.=
d) None of the above.

29) A decrease in the number of platelets is:
a) Thrombocytopenia.=
b) Thrombocytosis.
c) Thrombosis.
d) Thrombopoiesis.

30) …………………is the reduction in the amount of circulating Hemoglobin,red blood cells or both:
a) Polycythemia.
b) Anemia.=
c) Hemophila.
d) Leukopenia.


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